1 base, abject, contemptible, debased, degenerate, depraved, bad, iniquitous, execrable, atrocious, sordid, immoral, amoral, wicked, evil, sinful, hellish, fiendish, ignoble, revolting, despicable, horrid, horrible, dreadful, terrible, corrupt, mean, wretched, miserable, degrading, ignominious, disgraceful, shameful, shameless:
In every age, the vilest specimens of human nature are to be found among demagogues.
2 disgusting, nasty, sickening, nauseous, nauseating, foul, loathsome, offensive, noxious, repulsive, repellent, repugnant:
It is, indeed, a vile disease, but at least it is not contagious. She had prepared some vile cocktail that I refused to drink.