1 downfall, destruction, devastation, havoc, breakdown, breakup, débâcle, collapse, fall, disintegration, ruination, dissolution, wiping out, failure, decay, undoing, end; conquest, defeat, overthrow; bankruptcy, liquidation, failure:
Alexander was responsible for the ruin of the Persian empire. Overwhelming debts spelt Theo's financial ruin
2 degradation, dishonour, debasement, defilement, corruption, vitiation, seduction, degrading, dishonouring, debasing, defiling, corrupting, vitiating, seducing; deflowering, defloration:
Who was the libertine who brought about the ruin of Lord Harecombe's daughter?
3 nemesis, curse, end, bane, curse:
That boy will be my ruin!
4 gin, mother's ruin, blue ruin, Slang rot-gut:
After eating, we sat down and polished off a bottle of mother's ruin.
5 hag, witch, crone, beldam; dotard, (old) fogy or fogey, fossil, fuddy-duddy, antique, Brit OAP (= 'old-age pensioner'), Chiefly US retiree, Colloq (old) geezer, wreck, Slang dodo:
It's hard to understand what those two old ruins see in each other.
6 ruins. debris, wreckage, fragments, rubble, remains:
He stood among the ruins of the burnt-out house wondering what to do next. She was trying to piece together the ruins of her disastrous marriage.
7 destroy, devastate, demolish, annihilate, dissolve, wipe out, undo, overthrow, lay waste, raze, shatter, wreck, crush, flatten, wreak havoc (up)on, reduce to nothing or naught, pulverize, smash, bring to ruin:
The bomb ruined the entire centre of the city.
8 spoil, disfigure, damage, botch, mess up, make a mess of, mar, uglify:
The county office building completely ruins the Aylesbury skyline.
9 spoil, destroy, wreck, nullify, damage, harm, hurt, impair, poison, Slang louse up, screw up, put the kibosh on, US bollix up, Taboo Slang chiefly Brit make a balls-up of:
I think that your behaviour at the office party may just have ruined your prospects for promotion
10 bankrupt, pauperize, impoverish, reduce to penury or poverty or destitution or indigence:
Paying off the loan virtually ruined me.
11 violate, deflower, ravish, seduce, lead astray, dishonour, defile, corrupt, debase, defile:
She claimed that it was the local squire who ruined her, despite evidence to the contrary.