1 puncture, pinhole, pinprick; hole, perforation:
For the blood test, the doctor made a tiny prick in my finger with a needle
2 sting, pinch, twinge, prickle, tingle, pain:
The teacher leapt from her chair the instant she felt the prick of the tack.
3 puncture, pierce, stab, jab, punch, perforate, riddle; lance:
Using a pin, prick tiny holes in the paper to let the steam escape. The doctor pricked a boil on my neck
4 stab, sting, hurt, prickle, pinch, bite, smart:
The hypodermic needle really pricked me when it went in.