1 almost, (very) nearly, wellnigh, virtually, in effect, just about, essentially, fundamentally, at bottom, basically, when all is said and done, at the end of the day, to all intents and purposes:
We are practically there. I have practically finished the ironing.
2 realistically, matter-of-factly, clearly, simply, reasonably, rationally, sensibly:
Practically, there was nothing to be done except let the fire burn itself out.