1 handle, administer, run, supervise, look after, watch over, direct, head, oversee, superintend, direct, preside over, be in charge (of), take care of, control; rule (over), govern, regulate:
Mr Grant manages the glove department.
2 handle, cope or deal with, control, govern, manipulate:
Will you be able to manage such a frisky horse?
3 conduct, carry on, carry out, bring off, control, undertake, take care of, look after, handle:
Is she old enough to manage her own affairs?
4 succeed, function, make do, make it, shift (for oneself), get along or by or on, make out, muddle through, survive:
Will you be able to manage from here on?