1 gone, departed, vanished, strayed; missing, mislaid, misplaced, irrecoverable:
They found my lost dog. The airline told me that my bag was lost.
2 wasted, misspent, gone by the board, squandered, down the drain, spent, exhausted, Colloq out of the window:
The new arrangement is resulting in a lot of time lost. I watched another lost opportunity slip by.
3 confused, baffled, perplexed, puzzled, mystified, bewildered, confounded, adrift, helpless, disoriented, at sea, astray:
I am totally lost when it comes to high finance.
4 forgotten, bygone, extinct, past, obsolete, vanished, buried:
Good writing needn't be a lost art.
5 dead, extinct, departed, fallen, late:
We held a memorial service for our lost comrades.
6 destroyed, demolished, devastated, ruined, wrecked, irreparable, unsalvageable, irreclaimable, irremediable:
After the exposé in the newspaper, his name was consigned to the limbo of lost reputations
7 damned, cursed, accursed, abandoned, corrupt, fallen, wanton, unchaste, dissolute:
Unrepentant sinners are lost souls.
8 hopeless, distraught, distracted, desperate, frantic, frenzied:
He had the lost look of a cornered fugitive.