1 mislay, misplace, displace, part with; suffer the loss of, be deprived of:
I lost my pen. He lost a leg in the war.
2 forfeit, yield:
He says he lost the rent money gambling.
3 give up, yield, capitulate, admit defeat, succumb, bow to, be defeated or conquered, suffer defeat, be beaten or overcome or worsted or bested, Colloq lose out:
It was a good game, but we lost.
4 waste, let slip, squander, dissipate, fritter or trifle away, run out of; consume, use (up), expend, spend:
We lost a lot of time waiting for him to decide.
5 elude, evade, escape, throw or shake off, give the slip:
I managed to lose the sinister-looking man who was shadowing me.