1 tickle, tingle, prickle:
These mosquito bites itch terribly.
2 desire, crave, hanker, hunger, thirst, yearn, pine, wish, want, die:
I am itching to get my hands on whoever told you that I was dead.
3 tickle, tickling, tingle, tingling, prickle, prickling, irritation:
My frustration is like having an itch I can't scratch.
4 desire, craving, hankering, hunger, thirst, yearning, longing, Colloq yen:
I have a sudden itch to visit mother for the weekend.