1 take wing, take flight, take to the air, wing, soar, sail, hover; flutter, flit, flap:
A stork flew overhead. Daedalus taught Icarus to fly.
2 Also, fly away or off. take flight, depart, leave, flee, decamp, bolt, run away or off, escape, make (good) one's escape, take to one's heels, show a clean pair of heels, rush or nip off or out or away, (make a) run (for it), go or get away or off, abscond, make a getaway, cut and run, beat a (hasty) retreat, take off, scoot, Colloq light out, beat it, clear out or off, skedaddle, scram, US cut out, hightail (it), take it on the lam, take a (run-out) powder, lam out, take to the hills, take to the woods; Slang Brit scarper, bugger off, US vamoose, blow:
She flew off before I could get her telephone number.
3 hasten, hurry, rush, run, race, dash, sprint, tear, scamper, scoot, Colloq make tracks:
I must fly if I'm to catch the train.
4 pass (by), elapse, go (by), expire, run its course, slip or slide by or away:
Time flies quickly when you're having fun.
5 aviate, pilot; jet:
Parker flies his own plane. I flew down to Paris with him.
6 fly in the face of. flout, defy, go against, contemn, scorn, scoff at, oppose, go or run counter to, counter, counteract, countervail, countermine, contradict, contravene, thumb one's nose at, Colloq Brit cock a snook at:
His actions fly in the face of conventional behaviour.
7 fly off the handle. fly into a rage or fury or temper or passion, lose one's temper, have a fit or tantrum, be fit to be tied, go berserk, go crazy or mad, explode, Colloq lose or blow one's cool, blow one's top, hit or go through the roof, US hit the ceiling, blow one's stack, get worked up (over); Slang blow a fuse or a gasket, flip (one's lid), have a haemorrhage, Brit flip one's top:
Rudolf flies off the handle at the slightest provocation.
8 let fly.
(a) throw, toss, cast, hurl, fling, heave, pitch, lob, sling, chuck, shoot, fire (off), let rip, discharge, launch, propel, let go or off:
They let fly a volley of arrows.
(b) let go with, let (someone) have it, lash out, vent one's spleen, lose one's temper, burst out or forth, burst into, Colloq pull no punches, tear into:
That was the last straw, and she really let fly at him.
9 Often, Brit flies. flap, fly front, Brit zip, US zipper:
He was embarrassed to find his flies were open.
10 fly in the ointment. hitch, snag, impediment, obstacle, obstruction, problem, difficulty, drawback, detraction, rub, hindrance, bugbear, bogey, bugaboo, Offensive nigger in the woodpile:
The one fly in the ointment is that my mother won't give me permission to go.