1 malediction, imprecation, denunciation, damnation, execration, oath:
He heaped curses on all those who opposed him.
2 evil, bane, misfortune, affliction, torment, harm, scourge, cross to bear:
The curse of our generation is that so few of us deeply believe anything.
3 profanity, oath, blasphemy, obscenity, bad language, dirty word, swear-word, curse-word:
A stream of curses issued from the bathroom when Joe cut himself shaving.
4 damn, execrate, blast, denounce, anathematize, excommunicate:
He was cursed by the priests and forbidden ever to enter a temple again.
5 swear at, blaspheme at:
The muleteer was cursing his team.
6 burden, saddle, weigh down, handicap:
She was cursed with bad eyesight and had to wear thick glasses.